HeathImpactAI

Managing systemic lupus erythematosus (SLE) often means navigating periods of stability interrupted by sudden symptom spikes. These episodes—called lupus flare triggers—are both co mmon and highly disruptive. Studies estimate that between 60% and 90% of people with SLE experience at least one flare per year, and nearly one-third experience frequent flares that significantly impair quality of life.

Fatigue is one of the most pervasive and frustrating aspects of lupus. Up to 90% of patients experience significant exhaustion, and surveys consistently show that fatigue impacts quality of life more than pain or mobility issues. Understanding lupus fatigue causes is essential because fatigue can be driven by multiple co-existing factors.

Kidney involvement—known as lupus nephritis—affects up to half of people with lupus. Because lupus kidney damagecan progress silently, early detection is critical. Research shows that patients who begin treatment before significant proteinuria or fibrosis develops have significantly better long-term outcomes.